現貨moradec AH-101-AF說明書

更新時間：2022-12-28

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現貨moradec AH-101-AF說明書

αHFc NC MMAF

抗人IgG Fc MMAF抗體與不可裂解連接子

目錄號：AH-101-AF

αHFc NC MMAF是一種抗人IgG Fc特異性抗體，其與單甲基auristatin F（MMAF）結合，具有不可裂解的接頭。抗體部分是對人IgG的Fc區特異的多克隆抗體。單甲基auristatin F（MMAF）是一種細胞毒性小分子，通過阻斷微管蛋白的聚合來抑制細胞分裂。連接MMAF和抗體的不可裂解接頭在細胞外液中是穩定的，但在進入細胞時可以通過未指明的機制裂解。

αHFc-NC-MMAF

Anti-human IgG Fc-MMAF Antibody with Non-Cleavable Linker

Catalog Number: AH-101-AF

αHFc-NC-MMAF is anti-human IgG Fc specific antibody conjugated to monomethyl auristatin F (MMAF) with a non-cleavable linker. The antibody portion is a polyclonal antibody which is specific to the Fc region of human IgGs. Monomethyl auristatin F (MMAF) is a cytotoxic small molecule which inhibits cell division by blocking the polymerization of tubulin. The non-cleavable linker connecting MMAF to the antibody is stable in extracellular fluid, but can be cleaved by unspecified mechanisms upon entering cells.

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